PDx-POP®

PDx POP is ICON’s software tool for expediting the iterative process of population pharmacokinetic modeling and analysis.

PDx-Pop® software provides an easy to use graphical user interface to expedite the iterative process of population pharmacokinetic modeling and analysis. Working in concert with NONMEM®, the "gold standard" in Population Pharmacokinetic and Pharmacokinetic-Pharmacodynamic modeling, MS Excel® and R or S-PLUS® Analytic Software, PDx-Pop delivers optimal flexibility, increased efficiency and added functionality.

Features:

Windows Vista, Linux and Mac OS X compatibility
Improved Modeling Management
Enhanced Data Management and Exploration
Real time plotting of objective function value to monitor progress graphically.
Efficient Post-Processing
Enhanced Report-Friendly Outputs
Automated Model Evaluation Methods
Tracking and Audit Trail
Detailed Help System
Automated plots for individual parameter estimates (QQ-plots, QQ-log plots, and histograms of parameters)
Automated plots for individual eta estimates (pairs plots, QQ-Plots and histograms of etas)

New features available in PDx-POP Verion 3.2:

PDx-POP 3.2 is designed for use with NONMEM V and VI;
Ability to use multiple CPUs on multi-processor systems for batched runs.

System Requirements

Recommended system requirements to run PDx-POP with other required software:
- Intel or AMD pentium processor with 1 GB of memory (2 GB for Windows Vista)
- Windows 2000, XP, or Vista, Linux (Ubuntu, Redhat tested), or Mac OS X (Tiger tested)
- Graphics card and monitor capable of minimum resolution of 1280x800
- SuperVGA or other Windows-compatible graphics card and monitor
- CD-ROM disk drive
- Microsoft mouse or other compatible pointing device
- Supports all compatible printers
- 100 MB free disk space for all required software (Interface space = 25 MB)
- 100 MB of swap space/virtual memory

Required Software

NONMEM V Level 1.1 or higher:
Compaq/Digital Visual Fortran (Versions 5.0 through 6.6), Intel Fortran 7.x - 10.x for Windows, or GNU g95, gfortran
MS Excel 97 or higher and Word 97or higher
Internet Explorer 6.0 or higher or other browser

NONMEM 7 or higher:
Intel Fortran compiler 8.0 or higher, or GNU g95, gfortran
MS Excel 97 or higher and Word 97or higher
Internet Explorer 6.0 or higher or other browser

Recommended Software

R version 2.5.0 (or higher) or S-PLUS for Windows 6.1 (or higher)
(required for model evaluation features).
Xpose 4.0 for R or 3.104 for S-Plus (available at http://xpose.sourceforge.net/).

*Intel Visual Fortran requires Microsoft Visual Studio.

Licensing

PDx-POP seat licenses are purchased on an annual basis. The base unit of purchase is a 3-seat annual license, with the ability to purchase individual annual seat licenses after base purchase for that year. PDx-Pop licensees are entitled to the following benefits:

Full customer support
Automatic updates and upgrades, exclusive of new functionality
Advanced notice and priority shipment of new products and version releases