ICON’s can answer a range of questions that may arise during product portfolio review using a variety of approaches, including retrospective studies, economic modeling, literature review, and expert interviews:

• What is the patient or care giver burden of illness?
• What is the cost of existing treatments?
• What is the potential impact of a new drug on costs of treatment?
• What are the current provider practice patterns for this disease?
• What is the current reimbursement environment for a potential product?
• What is the impact of regional and national policy on product adoption?
• What economic and patient reported outcomes are likely to be needed?
• What is the potential impact of alternative pricing or reimbursement plans?